Ankle Replacement Arthroplasty

Ankle Replacement Arthroplasty Market Outlook

The global Ankle Replacement Arthroplasty market is poised to witness substantial growth, with its market size expected to reach approximately USD 1.2 billion by 2035, expanding at a compound annual growth rate (CAGR) of around 7.9% from 2025 to 2035. The growing prevalence of ankle-related disorders, particularly among the aging population, is a significant factor driving this growth. Additionally, advancements in surgical techniques and implant technologies that enhance the longevity and performance of ankle implants are contributing to the increasing adoption of ankle replacement procedures. Moreover, the rising demand for minimally invasive surgeries is pushing healthcare facilities to invest in more sophisticated surgical solutions, which in turn, supports market expansion. As patients increasingly seek solutions that offer improved mobility and pain relief, the Ankle Replacement Arthroplasty market is expected to flourish in the coming years.

Growth Factor of the Market

The Ankle Replacement Arthroplasty market is significantly influenced by various growth factors, primarily the increasing incidence of osteoarthritis and rheumatoid arthritis, which are leading causes of ankle joint deterioration. As the global population ages, the demand for joint reconstruction surgeries is surging, thereby boosting the market. Furthermore, rising awareness among patients regarding new surgical options and enhanced recovery post-surgery is encouraging individuals to consider ankle replacements as viable solutions. Technological innovations such as the development of advanced implant materials and designs, including custom-fit options, are also enhancing surgical outcomes and patient satisfaction. In addition, healthcare reforms and the expansion of insurance coverage for joint replacement procedures are making these surgeries more accessible, further driving market growth. Finally, the rise in sports-related injuries is leading to a higher number of ankle surgeries, contributing positively to the market dynamics.

Key Highlights of the Market

• Expected market growth reaching USD 1.2 billion by 2035 with a CAGR of 7.9%.
• Surge in demand due to increasing prevalence of ankle disorders, especially among the elderly.
• Emergence of minimally invasive surgical techniques enhancing patient recovery.
• Technological advancements in implant materials and designs improving surgical outcomes.
• Rising awareness of orthopedic health and treatment options among patients.

By Product Type

Fixed-Bearing Ankle Implants:

Fixed-bearing ankle implants are designed to provide stability and support to the ankle joint. These implants are characterized by a fixed polyethylene bearing that attaches securely to the bone structure. The growing adoption of fixed-bearing designs can be attributed to their proven track record of success, lower wear rates, and favorable outcomes in younger, more active patients. With the increasing focus on patient satisfaction and longevity of the implants, manufacturers are dedicating research and development efforts towards enhancing the designs of fixed-bearing implants. This segment is expected to capture a significant share of the ankle replacement market as more orthopedic surgeons recommend these implants for their reliability and performance.

Mobile-Bearing Ankle Implants:

Mobile-bearing ankle implants allow for a degree of movement between components, which can mimic the natural motion of the ankle joint, potentially leading to a more natural gait. This type of implant enhances the range of motion and can reduce the risk of implant wear over time. The growing popularity of mobile-bearing designs can be attributed to advancements in materials and engineering that allow for smoother articulation. As patients increasingly seek options that provide greater mobility and comfort, mobile-bearing implants are becoming an attractive choice for both surgeons and patients alike. This trend is further supported by clinical studies indicating positive outcomes associated with mobile-bearing implants.

Anatomical Ankle Implants:

Anatomical ankle implants are designed to replicate the natural shape and biomechanics of the ankle joint, providing a more individualized solution for patients. These implants are tailored to suit the specific anatomical features of each patient, leading to improved fit and function. The demand for anatomical implants is on the rise, driven by the increasing recognition of the importance of personalized treatment in orthopedic surgeries. As the awareness of custom solutions grows, this segment is likely to see significant growth in the Ankle Replacement Arthroplasty market. The ability to customize implants enhances surgical outcomes, reduces complications, and improves patient satisfaction, making anatomical implants a preferred choice for many orthopedic surgeons.

Reverse Ankle Implants:

Reverse ankle implants are a novel approach in ankle arthroplasty, designed for patients with severe joint degeneration where traditional implants may not be effective. These implants allow for a different alignment and leverage mechanics, which can be particularly beneficial for patients with unique anatomical challenges. The reverse design also aims to enhance stability and improve functionality post-surgery. As the field of orthopedic surgery continues to advance, reverse ankle implants are gaining traction among surgeons and patients alike, thereby contributing to the growth of the market. This segment is expected to expand as more evidence supporting the effectiveness of reverse ankle implants becomes available.

Custom Ankle Implants:

Custom ankle implants are specifically designed and manufactured for individual patients based on their unique anatomy. The growing trend towards personalized healthcare is propelling the adoption of custom implants as they offer a precise fit and function, ultimately leading to better surgical outcomes. The ability to tailor implants to the patient’s needs enhances comfort and reduces recovery time, aligning well with the increasing demand for minimally invasive procedures. As technology continues to evolve, including advancements in 3D printing and imaging techniques, the custom implants segment is anticipated to grow significantly, making it a key player in the Ankle Replacement Arthroplasty market.

By Application

Hospitals:

Hospitals are the primary setting for ankle replacement surgeries, offering comprehensive care and specialized surgical teams. The availability of advanced surgical facilities and technology in hospitals contributes to their dominance in the application segment. Moreover, hospitals often have the capacity to handle complex cases and complications, making them a favored choice for patients requiring ankle arthroplasty. The growing volume of orthopedic surgeries conducted in hospital settings is expected to drive the demand for ankle replacement products, as hospitals continue to invest in advanced surgical instruments and implant technologies to improve patient outcomes.

Ambulatory Surgical Centers:

Ambulatory surgical centers (ASCs) are becoming an increasingly popular option for patients seeking ankle replacement surgeries, due to their focus on outpatient procedures and shorter recovery times. These centers provide patients with a convenient and less expensive alternative to traditional hospital settings. With advancements in minimally invasive techniques, ASCs are now equipped to handle ankle replacement surgeries with enhanced safety and efficiency. The convenience of same-day discharge and reduced hospital stays significantly appeals to patients, contributing to the growth of this segment in the Ankle Replacement Arthroplasty market. As more ASCs gain accreditation and adopt state-of-the-art surgical technologies, their market share is expected to expand.

Orthopedic Clinics:

Orthopedic clinics play a crucial role in the Ankle Replacement Arthroplasty market, providing specialized care tailored to patients with ankle conditions. These clinics often have dedicated orthopedic surgeons with expertise in ankle surgeries, ensuring high-quality care and personalized treatment plans. As patients seek expert opinions on their ankle injuries and conditions, the demand for ankle replacement solutions is likely to rise within these clinics. Furthermore, the trend towards non-invasive diagnostic techniques and rehabilitation services in orthopedic clinics enhances their ability to provide comprehensive care, thereby solidifying their position in the market.

Others:

This segment encompasses various healthcare settings that facilitate ankle replacement surgeries, including rehabilitation centers and specialty orthopedic hospitals. These facilities offer a range of services, from surgical interventions to post-operative rehabilitation, ensuring that patients have access to holistic care throughout their recovery journey. The variety of options in the 'Others' category is expected to grow as healthcare systems evolve and adapt to patient needs. As the focus on patient-centered care continues to gain momentum, these alternative settings are likely to contribute to the overall demand for ankle replacement products, thereby playing a significant role in the market.

By Distribution Channel

Direct Sales:

Direct sales involve manufacturers selling their ankle replacement products directly to healthcare providers and institutions, eliminating intermediaries. This approach enables companies to establish stronger relationships with hospitals and clinics while allowing them to gain direct feedback on their products. Direct sales are favored for their potential to deliver better pricing structures and tailored solutions for customers. With the increasing demand for ankle replacement surgeries, manufacturers are increasingly adopting direct sales strategies to ensure their products are accessible to healthcare providers. This segment is expected to witness substantial growth, driven by the need for efficient distribution methods and enhanced customer engagement.

Distributor Sales:

Distributor sales refer to the distribution of ankle replacement products through third-party intermediaries. Distributors play a vital role in expanding the reach of manufacturers, providing logistical support and ensuring that products are available to a wider range of healthcare providers. The distributor sales channel is favored for its ability to streamline operations and manage inventory effectively, making it an attractive option for manufacturers looking to penetrate various markets. As the complexity and volume of ankle replacement surgeries increase, the reliance on distributor sales is also expected to grow, allowing companies to focus on their core competencies while benefiting from the extensive networks of their distributors.

By Material Type

Metal-on-Polyethylene:

Metal-on-polyethylene implant designs have been a standard in ankle replacement arthroplasties, offering a balance of strength and wear resistance. The use of metal components in combination with polyethylene bearings provides durability and minimizes the risk of wear debris generation. This material type is favored for its proven performance in knee and hip arthroplasties, leading to its adoption in ankle replacements as well. The growing demand for reliable and long-lasting implants among orthopedic surgeons is contributing to the continued preference for metal-on-polyethylene devices. As advancements in material science introduce improved polyethylene formulations, the market for this segment is expected to grow significantly.

Ceramic-on-Polyethylene:

Ceramic-on-polyethylene implants are gaining popularity due to their excellent wear characteristics and reduced risk of osteolysis. The use of ceramic components minimizes wear and tear when compared to traditional metal implants, offering enhanced longevity and potentially better patient outcomes. As the awareness of implant longevity and patient safety increases, orthopedic surgeons are increasingly recommending ceramic-on-polyethylene designs for ankle replacements. This segment is expected to grow as clinical evidence supporting the benefits of ceramic materials continues to emerge, along with advancements in manufacturing processes improving the availability of these implants.

Metal-on-Metal:

Metal-on-metal implants are characterized by their high strength and durability, making them a viable option for certain patients undergoing ankle replacements. While these designs have faced scrutiny due to potential wear and metal ion release, ongoing advancements in materials and engineering are enhancing their safety profiles. There is still a niche demand for metal-on-metal components among specific patient populations, particularly younger and more active individuals. As manufacturers address concerns related to wear debris and improve implant designs, the metal-on-metal segment may see a revival in the market, appealing to patients seeking robust and long-lasting solutions.

Ceramic-on-Ceramic:

Ceramic-on-ceramic implants represent a cutting-edge material option that offers minimal wear and a low risk of allergic reactions. This design provides exceptional durability and is particularly suited for younger patients who may require long-lasting solutions. The advantages of ceramic-on-ceramic implants, such as their biocompatibility and superior mechanical properties, are driving their adoption in ankle replacement surgeries. As clinical outcomes utilizing ceramic materials continue to prove favorable, this segment is expected to grow significantly, appealing to both surgeons and patients who prioritize the longevity and safety of their implants.

Others:

The 'Others' segment encompasses alternative materials and composite designs used in ankle replacement implants, including hybrid systems that combine various material properties to enhance performance. This is an innovative area where manufacturers are exploring various combinations to achieve optimal outcomes, addressing specific patient needs and preferences. The ongoing research and development in this segment are likely to fuel growth as new materials emerge that can offer better biocompatibility, reduced wear rates, and improved functionality for ankle replacements. As the industry moves towards more personalized solutions, innovations within this segment are anticipated to play a crucial role in the overall market dynamics.

By Region

The regional analysis of the Ankle Replacement Arthroplasty market reveals distinct growth trajectories and trends across different geographical areas. North America currently dominates the market, accounting for approximately 45% of the total share, driven by the high prevalence of ankle diseases, advanced healthcare infrastructure, and the presence of key industry players. The region is expected to grow at a CAGR of 7.5% during the forecast period, fueled by rising healthcare expenditures and an increasing number of outpatient surgical centers. Meanwhile, Europe holds a significant share as well, attributed to a growing aging population and continuous advancements in orthopedic technologies. The European market is projected to witness steady growth, driven by the increasing adoption of innovative surgical techniques and implant designs.

In contrast, the Asia Pacific region is expected to exhibit the highest growth rate, with a CAGR of around 9.4% over the forecast period. Factors such as rising disposable incomes, increasing awareness of orthopedic health, and expanding healthcare access are contributing to the surge in demand for ankle replacement surgeries in this region. Additionally, growing investments in healthcare infrastructure and burgeoning economies in countries like China and India are anticipated to further propel the market. Latin America and the Middle East & Africa represent emerging markets that are gradually gaining traction due to ongoing improvements in healthcare systems and increasing patient awareness about advanced treatment options. Overall, as the global demographics shift and healthcare accessibility improves, regional dynamics will play a crucial role in shaping the future of the Ankle Replacement Arthroplasty market.

Opportunities

The Ankle Replacement Arthroplasty market presents numerous opportunities for growth, particularly with the advancement of new technologies and surgical techniques. One of the most significant opportunities lies in the development of minimally invasive surgical methods, which can reduce recovery times and improve patient outcomes. As healthcare professionals increasingly favor these techniques, manufacturers have the chance to design implants that cater specifically to minimally invasive procedures. Additionally, the rise in telemedicine and remote patient monitoring can enhance post-surgical care, creating opportunities for companies to integrate their products with digital health solutions to ensure better patient management. These developments not only enhance patient satisfaction but also open up avenues for collaboration between technology firms and healthcare providers in the orthopedic space.

Furthermore, there is a growing market for personalized implants and custom-fit solutions as patients seek more tailored healthcare experiences. Advancements in imaging technologies and 3D printing are enabling manufacturers to create implants that match the unique anatomy of each patient, which can lead to improved surgical outcomes and satisfaction. This trend towards personalized medicine is expected to drive innovation in the Ankle Replacement Arthroplasty market, allowing companies to differentiate themselves through unique product offerings. As awareness continues to grow regarding the importance of individualized treatment plans, companies that embrace this approach are likely to find a competitive edge in the evolving market landscape.

Threats

The Ankle Replacement Arthroplasty market faces several potential threats that could hinder its growth. One significant concern is the potential for complications associated with surgical procedures, including infection, implant failure, and the need for revision surgeries. Such complications can lead to negative patient outcomes and could discourage individuals from opting for ankle replacement surgery. Additionally, the market is subject to stringent regulatory requirements and post-market surveillance that can delay product launches and increase costs for manufacturers. Ensuring compliance with these regulations can be resource-intensive, potentially limiting the entry of new players into the market and hindering innovation. Furthermore, the fluctuating economic conditions and changes in healthcare policies globally may impact the spending capabilities of healthcare facilities and patients alike, thereby influencing market dynamics.

Another major challenge facing the Ankle Replacement Arthroplasty market is the growing competition from alternative treatment options. Non-surgical interventions, such as physiotherapy and pain management techniques, are becoming increasingly popular for managing ankle-related disorders. Patients may opt for these less invasive options to avoid surgery, which could limit the growth of the ankle replacement market. Moreover, the emergence of innovative treatment modalities and technologies could also divert funding and attention away from traditional ankle replacement procedures, posing a competitive threat. As the market continues to evolve, stakeholders must remain vigilant and adapt to these challenges to sustain growth and maintain their market positions.

Competitor Outlook

• DePuy Synthes (Johnson & Johnson)
• Stryker Corporation
• Zimmer Biomet Holdings, Inc.
• Smith & Nephew plc
• Wright Medical Group N.V. (part of Stryker)
• ConvaTec Group PLC
• Medtronic plc
• Exactech, Inc.
• NuVasive, Inc.
• Arthrex, Inc.
• Boston Scientific Corporation
• Integra LifeSciences Corporation
• Orthofix Medical Inc.
• Hanger, Inc.
• Corin Group PLC

The competitive landscape of the Ankle Replacement Arthroplasty market is characterized by a diverse range of players, ranging from established multinational corporations to emerging startups. Major companies such as DePuy Synthes, Stryker Corporation, and Zimmer Biomet dominate the market, leveraging their extensive research capabilities, distribution networks, and established brand reputations to capture market share. These companies invest significantly in research and development to innovate and improve their product offerings, ensuring they remain at the forefront of the industry. Their robust marketing strategies and collaborations with healthcare providers further enhance their competitive positions, enabling them to address the evolving needs of patients and surgeons alike.

Additionally, the market is witnessing the entry of niche players and startups that focus on developing specialized ankle implants and advanced surgical techniques. These companies often bring fresh perspectives and innovative solutions to the table, challenging traditional players and driving competition. For instance, some startups are focusing on 3D printing technologies to create personalized implants that cater to individual patient anatomy, which can lead to better outcomes and increased patient satisfaction. The rise of these innovative players is contributing to a dynamic market environment, where established companies must continuously adapt to maintain their competitive edge while also responding to the demands of a rapidly evolving healthcare landscape.

Moreover, key players are forming strategic partnerships and collaborations to enhance their market presence and expand their product portfolios. Collaborations between manufacturers and research institutions are paving the way for the development of next-generation ankle implants, addressing unmet patient needs and improving surgical outcomes. Similarly, partnerships with healthcare providers enable companies to better understand market demands and streamline their product offerings accordingly. As the Ankle Replacement Arthroplasty market continues to grow, the focus on collaboration and innovation will be essential for companies aiming to thrive in this competitive landscape.

• 1 Appendix

  • 1.1 List of Tables
  • 1.2 List of Figures

• 2 Introduction

  • 2.1 Market Definition
  • 2.2 Scope of the Report
  • 2.3 Study Assumptions
  • 2.4 Base Currency & Forecast Periods

• 3 Market Dynamics

  • 3.1 Market Growth Factors
  • 3.2 Economic & Global Events
  • 3.3 Innovation Trends
  • 3.4 Supply Chain Analysis

• 4 Consumer Behavior

  • 4.1 Market Trends
  • 4.2 Pricing Analysis
  • 4.3 Buyer Insights

• 5 Key Player Profiles

  • 5.1 Hanger, Inc.
    • 5.1.1 Business Overview
    • 5.1.2 Products & Services
    • 5.1.3 Financials
    • 5.1.4 Recent Developments
    • 5.1.5 SWOT Analysis
  • 5.2 Arthrex, Inc.
    • 5.2.1 Business Overview
    • 5.2.2 Products & Services
    • 5.2.3 Financials
    • 5.2.4 Recent Developments
    • 5.2.5 SWOT Analysis
  • 5.3 Medtronic plc
    • 5.3.1 Business Overview
    • 5.3.2 Products & Services
    • 5.3.3 Financials
    • 5.3.4 Recent Developments
    • 5.3.5 SWOT Analysis
  • 5.4 Exactech, Inc.
    • 5.4.1 Business Overview
    • 5.4.2 Products & Services
    • 5.4.3 Financials
    • 5.4.4 Recent Developments
    • 5.4.5 SWOT Analysis
  • 5.5 NuVasive, Inc.
    • 5.5.1 Business Overview
    • 5.5.2 Products & Services
    • 5.5.3 Financials
    • 5.5.4 Recent Developments
    • 5.5.5 SWOT Analysis
  • 5.6 Corin Group PLC
    • 5.6.1 Business Overview
    • 5.6.2 Products & Services
    • 5.6.3 Financials
    • 5.6.4 Recent Developments
    • 5.6.5 SWOT Analysis
  • 5.7 ConvaTec Group PLC
    • 5.7.1 Business Overview
    • 5.7.2 Products & Services
    • 5.7.3 Financials
    • 5.7.4 Recent Developments
    • 5.7.5 SWOT Analysis
  • 5.8 Smith & Nephew plc
    • 5.8.1 Business Overview
    • 5.8.2 Products & Services
    • 5.8.3 Financials
    • 5.8.4 Recent Developments
    • 5.8.5 SWOT Analysis
  • 5.9 Stryker Corporation
    • 5.9.1 Business Overview
    • 5.9.2 Products & Services
    • 5.9.3 Financials
    • 5.9.4 Recent Developments
    • 5.9.5 SWOT Analysis
  • 5.10 Orthofix Medical Inc.
    • 5.10.1 Business Overview
    • 5.10.2 Products & Services
    • 5.10.3 Financials
    • 5.10.4 Recent Developments
    • 5.10.5 SWOT Analysis
  • 5.11 Zimmer Biomet Holdings, Inc.
    • 5.11.1 Business Overview
    • 5.11.2 Products & Services
    • 5.11.3 Financials
    • 5.11.4 Recent Developments
    • 5.11.5 SWOT Analysis
  • 5.12 Boston Scientific Corporation
    • 5.12.1 Business Overview
    • 5.12.2 Products & Services
    • 5.12.3 Financials
    • 5.12.4 Recent Developments
    • 5.12.5 SWOT Analysis
  • 5.13 Integra LifeSciences Corporation
    • 5.13.1 Business Overview
    • 5.13.2 Products & Services
    • 5.13.3 Financials
    • 5.13.4 Recent Developments
    • 5.13.5 SWOT Analysis
  • 5.14 DePuy Synthes (Johnson & Johnson)
    • 5.14.1 Business Overview
    • 5.14.2 Products & Services
    • 5.14.3 Financials
    • 5.14.4 Recent Developments
    • 5.14.5 SWOT Analysis
  • 5.15 Wright Medical Group N.V. (part of Stryker)
    • 5.15.1 Business Overview
    • 5.15.2 Products & Services
    • 5.15.3 Financials
    • 5.15.4 Recent Developments
    • 5.15.5 SWOT Analysis

• 6 Market Segmentation

  • 6.1 Ankle Replacement Arthroplasty Market, By Application
    • 6.1.1 Hospitals
    • 6.1.2 Ambulatory Surgical Centers
    • 6.1.3 Orthopedic Clinics
    • 6.1.4 Others
  • 6.2 Ankle Replacement Arthroplasty Market, By Product Type
    • 6.2.1 Fixed-Bearing Ankle Implants
    • 6.2.2 Mobile-Bearing Ankle Implants
    • 6.2.3 Anatomical Ankle Implants
    • 6.2.4 Reverse Ankle Implants
    • 6.2.5 Custom Ankle Implants
  • 6.3 Ankle Replacement Arthroplasty Market, By Material Type
    • 6.3.1 Metal-on-Polyethylene
    • 6.3.2 Ceramic-on-Polyethylene
    • 6.3.3 Metal-on-Metal
    • 6.3.4 Ceramic-on-Ceramic
    • 6.3.5 Others
  • 6.4 Ankle Replacement Arthroplasty Market, By Distribution Channel
    • 6.4.1 Direct Sales
    • 6.4.2 Distributor Sales

• 7 Competitive Analysis

  • 7.1 Key Player Comparison
  • 7.2 Market Share Analysis
  • 7.3 Investment Trends
  • 7.4 SWOT Analysis

• 8 Research Methodology

  • 8.1 Analysis Design
  • 8.2 Research Phases
  • 8.3 Study Timeline

• 9 Future Market Outlook

  • 9.1 Growth Forecast
  • 9.2 Market Evolution

• 10 Geographical Overview

  • 10.1 Europe - Market Analysis
    • 10.1.1 By Country
      • 10.1.1.1 UK
      • 10.1.1.2 France
      • 10.1.1.3 Germany
      • 10.1.1.4 Spain
      • 10.1.1.5 Italy
  • 10.2 Asia Pacific - Market Analysis
    • 10.2.1 By Country
      • 10.2.1.1 India
      • 10.2.1.2 China
      • 10.2.1.3 Japan
      • 10.2.1.4 South Korea
  • 10.3 Latin America - Market Analysis
    • 10.3.1 By Country
      • 10.3.1.1 Brazil
      • 10.3.1.2 Argentina
      • 10.3.1.3 Mexico
  • 10.4 North America - Market Analysis
    • 10.4.1 By Country
      • 10.4.1.1 USA
      • 10.4.1.2 Canada
  • 10.5 Middle East & Africa - Market Analysis
    • 10.5.1 By Country
      • 10.5.1.1 Middle East
      • 10.5.1.2 Africa
  • 10.6 Ankle Replacement Arthroplasty Market by Region

• 11 Global Economic Factors

  • 11.1 Inflation Impact
  • 11.2 Trade Policies

• 12 Technology & Innovation

  • 12.1 Emerging Technologies
  • 12.2 AI & Digital Trends
  • 12.3 Patent Research

• 13 Investment & Market Growth

  • 13.1 Funding Trends
  • 13.2 Future Market Projections

• 14 Market Overview & Key Insights

  • 14.1 Executive Summary
  • 14.2 Key Trends
  • 14.3 Market Challenges
  • 14.4 Regulatory Landscape

Segments Analyzed in the Report

The global Ankle Replacement Arthroplasty market is categorized based on

By Product Type

• Fixed-Bearing Ankle Implants
• Mobile-Bearing Ankle Implants
• Anatomical Ankle Implants
• Reverse Ankle Implants
• Custom Ankle Implants

By Application

• Hospitals
• Ambulatory Surgical Centers
• Orthopedic Clinics
• Others

By Distribution Channel

• Direct Sales
• Distributor Sales

By Material Type

• Metal-on-Polyethylene
• Ceramic-on-Polyethylene
• Metal-on-Metal
• Ceramic-on-Ceramic
• Others

By Region

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa

Key Players

• DePuy Synthes (Johnson & Johnson)
• Stryker Corporation
• Zimmer Biomet Holdings, Inc.
• Smith & Nephew plc
• Wright Medical Group N.V. (part of Stryker)
• ConvaTec Group PLC
• Medtronic plc
• Exactech, Inc.
• NuVasive, Inc.
• Arthrex, Inc.
• Boston Scientific Corporation
• Integra LifeSciences Corporation
• Orthofix Medical Inc.
• Hanger, Inc.
• Corin Group PLC